Croscarmellose Sodium Superdisintegrant ee Kiniiniyada Daawada | Barar Degdeg ah, Heerka Isticmaalka Hoose 0.5-5% | USP/EP/JP oo u hoggaansan

Croscarmellose Sodium-keena waa superdisintegrant saafi ah oo loogu talagalay qaababka qiyaasta adag ee afka laga qaato oo ay ku jiraan kiniiniyada, kaabsulka, iyo granules. Waa sodium carboxymethylcellulose oo gudaha ku xiran oo aan ku milmi karin biyaha laakiin si degdeg ah u barara ilaa 4-8 jeer mugga asalka ah marka uu la xiriiro biyo-mareenka.Qaab-dhismeedkan gaarka ah ee fiilooyinka leh wuxuu bixiyaa awood aad u fiican oo lagu nuugo biyaha iyo ficilka xididdada dhiigga, taasoo keenta kala-goyn kiniin oo heer sare ah iyo kala-goyn daroogo oo la xoojiyayWaxay la jaanqaadaysaa dawooyinka USP-NF, EP, JP, iyo ChP iyadoo la diiwaangelinayo CDE F20209990136Heerka isticmaalka caadiga ah: 0.5-5.0% w/w (2% cadaadis toos ah, 3% granulation qoyan)Ku habboon cadaadis toos ah, granulation qoyan (gudaha ama dibadda granular), isku-soo-ururinta duuban, iyo qaacidooyinka kaabsal

Nala soo xiriir

Faahfaahinta Badeecada

Sodium Croscarmellose oo ah nooca daawada (CCS)

Dulmar Guud oo ku saabsan Badeecada

Croscarmellose Sodium waa sodium carboxymethylcellulose oo gudaha ku xiran, oo si gaar ah loogu talagalay in loo isticmaalo sidii superdisintegrator qaab-dhismeedka dawooyinka.Si ka duwan kuwa burburiya waxyaabaha caadiga ah, waxay bixisaa sifooyin kala firdhisan oo heer sare ah, iyadoo hubinaysa burburka kiniinka si degdeg ah iyo kala firdhinta daawada oo la xoojiyay si loo wanaajiyo helitaanka noolaha .

Aqoonsiga Badeecada:

Magaca Kiimikada:Sodium Croscarmellose
Lambarka CAS:74811-65-7
Lambarka Diiwaangelinta CDE:F20209990136
U hoggaansanaanta Farmashiyaha:ChP, USP-NF, EP, JP, BP
Lambarka EC:629-739-2
Isku-mid ah:Carboxymethylcellulose oo isku xiran Sodium, CCNa, Sodium Croscarmellose, E468

Astaamaha Muhiimka ah & Faa'iidooyinka

1. Habka Kala-baxa Sare

Kala-goynta laba-fal:Waxay isku daraysaa ficilka xididdada dhiigga (duufaan) iyo barar degdeg ah
Bararid ilaa4-8 jeer muggeeda asalka ahmarka ay biyo taabtaan
Qaab-dhismeedka faybarku wuxuu bixiyaa awoodo nuugis biyo oo aad u fiican
Waxay abuurtaa ballaarin farsamo oo si dhakhso ah u kala jabisa kiniiniyada

2. Heerka Isticmaalka Hoose - Waxtar Sare

Wax ku ool ah marka la isku ururiyo sida ugu hooseeya0.5-5.0% w/w
Isticmaalka caadiga ah: 2% cadaadis toos ah, 3% granulation qoyan
Xal kharash-ool ah oo loogu talagalay horumarinta qaacidada

3. Dabacsanaanta Qaaciddada

Ku habboon dhammaan hababka kiniiniyada: cadaadis toos ah, granulation qoyan, isku-darka duubista
Qalabka qoyan ee granulation-ka, waxaa loo isticmaali karaa gudaha-granular, si ka baxsan-granular, ama loo qaybin karaa labada marxaladoodba
Ku habboon qaacidooyinka kaabsal (10-25% isticmaalka)

4. Sifooyinka Jireed ee Aad u Fiican

Muuqaalka:Budada cad ilaa caddaan, oo si xor ah u socota
Heerka Beddelka:0.60 – 0.85
Mugga Dejinta:10.0 – 30.0 ml
pH (1% xal):5.0 – 7.0
Lumis marka la qallajiyo:≤10.0%
Haraaga Shidista:14.0% – 28.0%
Walax ku milmi karta biyaha:≤10.0%
Biraha Culus:≤10 ppm

5. Iswaafajinta iyo Xasilloonida API

Miyuu sameeyaakuma jiraan peroxides- waxay hubisaa xasillooni wanaagsan oo loogu talagalay API-yada xasaasiga u ah oksaydhka
Saameyn xun kuma yeelanayso adkaanta kiniinka ama dabacsanaanta
Waxqabadka kala-goynta ayaa sii socda waqti ka dib
Aan ahayn GMO, oo aan lahayn xasaasiyad